Before You Begin
Question #45148
The Question
Read the following statements regarding the therapeutic applications of transgenic animals and the physiological basis of the targeted diseases. Which of the following statements is INCORRECT?
Options
- A.
Alpha-1-antitrypsin is a protease inhibitor produced via transgenic animals to prevent the proteolytic destruction of alveolar walls in emphysema.
- B.
The first transgenic cow, Rosie, was engineered to produce milk containing 2.4 grams per litre of human alpha-1-antitrypsin to treat chronic respiratory disorders.
- C.
Emphysema is a chronic respiratory disorder characterized by a decreased alveolar surface area, which can be exacerbated by a genetic deficiency of alpha-1-antitrypsin.
- D.
Transgenic animals serve as effective bioreactors because they can correctly fold and process complex human proteins, a feature often lacking in bacterial expression systems.
Check Your Answer
Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Regulatory_Failure
Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.
Concepts Behind This Question
Alpha-1 Antitrypsin|Transgenic Rosie|Emphysema
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: This question exploits a common 'Functional Confusion' trap.
Students frequently conflate the two major examples of transgenic animal products provided in the same paragraph of the NCERT Class 12 Biotechnology chapter: alpha-1-antitrypsin (used for emphysema) and human alpha-lactalbumin (produced by Rosie the cow).
By mixing the protein name, the animal, and the disease, it tests precise recall and differentiation of NCERT facts.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Biotechnology and Its Applications - Class 12 |
| Concept | Transgenic Animal Purpose |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |