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Question #45253
The Question
Read the following statements regarding the quiescent stage (G0) of the cell cycle and cellular regeneration. Which of the following statements is INCORRECT?
Options
- A.
Cells in the G0 phase remain metabolically active but do not proliferate unless required by the organism.
- B.
During compensatory hyperplasia of the liver, quiescent hepatocytes exit G0 and directly enter the S phase to rapidly duplicate their genome.
- C.
While adult neurons are permanently arrested in the G0 phase, hepatocytes can re-enter the G1 phase upon chemical or physical stimulation.
- D.
A diploid human hepatocyte arrested in the G0 phase possesses a DNA content of 2C and a chromosome number of 46.
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Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Evolutionary_Exception
Tackle problems where standard rules evolve or change based on specific environmental constraints.
Concepts Behind This Question
G0 Phase Quiescence|Metabolic Flux and Steady State|Cell Cycle and Cell Division
Why This Question Is Tricky
Common Mistakes
Process Sequence Trap.
The conceptual pivot relies on understanding the topological relationship between G0, G1, and S phases.
Students often assume that a 'call to proliferate' (like liver regeneration) triggers immediate DNA synthesis.
However, G0 is an offshoot of G1; thus, re-entry must occur through G1 to fulfill the metabolic and enzymatic prerequisites (metabolic flux) for the S phase.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Cell Cycle and Cell Division - Class 11 |
| Concept | G0 Phase Quiescence |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |