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Question #45447
The Question
During embryonic development, a targeted teratogen specifically destroys the upward evagination of the oral ectoderm (Rathke's pouch). If the fetus survives to adulthood, which of the following physiological responses to acute hypoglycemia will be most severely compromised?
Options
- A.
Facultative water reabsorption in the collecting duct mediated by a hypothalamic peptide.
- B.
Rapid hepatic glycogenolysis mediated by neural crest-derived catecholamines.
- C.
Hepatic gluconeogenesis stimulated by a steroid hormone acting via intracellular receptors.
- D.
Hepatic glycogenolysis stimulated by a pancreatic peptide hormone acting via membrane-bound receptors.
Check Your Answer
Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Regulatory_Failure
Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.
Concepts Behind This Question
Insulin|Glucagon|Adenohypophysis vs Neurohypophysis Origin
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: This question requires synthesizing three distinct NCERT concepts: Embryological origin (oral ectoderm vs. neuroectoderm), Endocrine axes (Hypothalamic-Pituitary-Adrenal axis), and Mechanism of Hormone Action (steroid/intracellular vs. peptide/membrane-bound).
The trap lies in recognizing that while glucagon and epinephrine also counter hypoglycemia, only the cortisol-mediated pathway (gluconeogenesis via intracellular receptors) is downstream of the oral ectoderm-derived adenohypophysis.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Chemical Coordination and Integration - Class 11 |
| Concept | Insulin vs Glucagon Effects |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |