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Question #45550
The Question
A 35-year-old male who underwent a bilateral vasectomy five years ago desires a biological child. The couple opts for Intracytoplasmic Sperm Injection (ICSI) using sperm retrieved via Testicular Sperm Extraction (TESE). Which of the following statements is CORRECT regarding the physiological principles underlying this procedure and subsequent embryonic development?
Options
- A.
Vasectomy induces irreversible cessation of spermatogenesis due to feedback inhibition; hence, TESE is only effective if performed within months of the sterilization.
- B.
Sperm retrieved via TESE bypass the need for capacitation in the female tract, and upon successful ICSI and blastocyst transfer, syncytiotrophoblast formation will proceed normally during implantation.
- C.
The syncytiotrophoblast will fail to secrete hCG because sperm extracted directly from the testis lack the necessary motility factors acquired in the vas deferens.
- D.
While ICSI overcomes the irreversible block in gamete transport, the resulting embryo requires artificial syncytiotrophoblast induction since natural fertilization pathways were bypassed.
Check Your Answer
Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Comparative_Analysis
Sharpen your ability to evaluate multiple scenarios and distinguish between competing potential answers.
Concepts Behind This Question
Spermatogenesis vs. Oogenesis Chronology|Implantation and Syncytiotrophoblast|ICSI Procedure
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: Students often confuse the interruption of gamete transport (vasectomy) with the cessation of gamete production (spermatogenesis).
Furthermore, a common misconception is that bypassing natural fertilization (via ICSI) alters the intrinsic developmental milestones of the embryo.
The question tests the understanding that syncytiotrophoblast formation is strictly dependent on successful blastocyst implantation, regardless of the gamete's transport history or the method of fertilization.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Reproductive Health - Class 12 |
| Concept | Sterilization Irreversibility |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |