Before You Begin
Question #45556
The Question
A hypothetical toxin selectively destroys the tight junctions between adjacent Sertoli cells in the seminiferous tubules of an adult male, while leaving the interstitial cells of Leydig completely unaffected. Which of the following would NOT be a clinical consequence of this exposure?
Options
- A.
Generation of an autoimmune response against haploid spermatozoa
- B.
Regression of secondary sexual characters such as facial hair and deep voice
- C.
Production of anti-sperm antibodies leading to gamete non-viability
- D.
Elevated levels of Follicle Stimulating Hormone (FSH) due to decreased inhibin secretion
Check Your Answer
Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Regulatory_Failure
Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.
Concepts Behind This Question
Sertoli Cell Functions|Infertility Definition|Blood-Testis Barrier
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: Students often conflate the functions of Sertoli and Leydig cells, assuming any severe testicular damage automatically causes a loss of testosterone.
This question requires synthesizing three distinct NCERT concepts: the immune privilege provided by the Blood-Testis Barrier, the specific endocrine feedback of the Inhibin-FSH axis, and the independent functional compartmentalization of Leydig cells (androgens) versus Sertoli cells (spermatogenesis support).
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Reproductive Health - Class 12 |
| Concept | Infertility Definition |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |