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Question #45557
The Question
A couple is evaluated for infertility after two years of unprotected coitus. Clinical records indicate that fertilization and implantation occur successfully, but the female experiences recurrent spontaneous abortions specifically around the 8th week of gestation. Which of the following endocrine anomalies is the most likely cause of this reproductive failure?
Options
- A.
Premature degeneration of the corpus albicans, leading to a sudden drop in endometrial progesterone.
- B.
Failure of the developing placenta to synthesize adequate progestogens during the luteal-placental shift.
- C.
Inadequate secretion of Luteinizing Hormone (LH) by the maternal anterior pituitary during the first trimester.
- D.
Insufficient production of human Placental Lactogen (hPL) by the trophoblast, preventing corpus luteum maintenance.
Check Your Answer
Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Regulatory_Failure
Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.
Concepts Behind This Question
Infertility Definition|Placental Endocrine Profile|Progesterone_Maintenance
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: Understanding the luteal-placental shift and the specific roles of placental hormones.
Students often confuse the roles of hCG, hPL, and LH, and fail to recognize that maternal pituitary LH is inactive during pregnancy.
Furthermore, it tests the clinical application that 'infertility' encompasses not just fertilization failure, but also the inability to maintain gestation due to placental endocrine insufficiency.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Reproductive Health - Class 12 |
| Concept | Infertility Definition |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |