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Question #45565

Difficulty: 8/10 | 🟢 Free

The Question

A 30-year-old female with patent fallopian tubes undergoes GIFT (Gamete Intrafallopian Transfer). The procedure fails because the donor's retrieved gametes were cytologically incompetent for in vivo fertilization. For a successful GIFT procedure, the transferred female gamete must be at which specific stage of oogenesis, and what physiological event is required to break its meiotic arrest in the recipient's ampulla?

Options

  • A.

    Secondary oocyte arrested at Metaphase II; entry of the sperm into the oocyte.

  • B.

    Primary oocyte arrested at Diplotene of Prophase I; the pre-ovulatory LH surge.

  • C.

    Secondary oocyte arrested at Anaphase II; completion of sperm capacitation.

  • D.

    Mature ovum having completed Meiosis II; fusion of male and female pronuclei.

Check Your Answer

Correct Answer

Step-by-Step Solution

Explanation

How the Examiner Thinks

Regulatory_Failure

Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.

Concepts Behind This Question

GIFT|Meiotic Arrest Points|Secondary Oocyte

Why This Question Is Tricky

Common Mistakes

Conceptual Pivot: Students often confuse the colloquial term 'ovum' used in Reproductive Health (GIFT) with its strict cytological identity in Human Reproduction (a secondary oocyte arrested at Metaphase II).

The trap relies on failing to distinguish between the two meiotic arrest points in oogenesis (Prophase I vs.

Metaphase II) and their specific triggers (LH surge vs.

Sperm entry).

Quick Facts About This Question

Question Information

SubjectBiology
ChapterReproductive Health - Class 12
ConceptGIFT Applicability
Difficulty8
Cognitive Load5
Target Solve Time120 sec
AccessFree