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Question #45800

Difficulty: 8/10 | 🟢 Free

The Question

In an ecosystem experiencing a severe drop in primary productivity, an apex predator faces a critical glucose deficit due to the 10% energy transfer law. During a sudden, intense sprint, its skeletal muscles rapidly fatigue due to a shift towards anaerobic glycolysis. Which of the following statements correctly identifies the molecular consequence of this metabolic shift on the sarcomere's cross-bridge cycle?

Options

  • A.

    The resulting accumulation of lactic acid lowers intracellular pH, causing H+ ions to interfere with Ca2+ binding to Troponin C and inhibiting myosin ATPase.

  • B.

    The rapid depletion of ATP prevents the binding of the energized myosin head to the exposed active sites on F-actin, halting the power stroke.

  • C.

    Anaerobic glycolysis produces excess CO2, which binds to the allosteric site of myosin ATPase, preventing the hydrolysis of ATP.

  • D.

    The lack of aerobic energy yield prevents the release of Ca2+ from the sarcoplasmic reticulum, keeping the tropomyosin-troponin complex bound to the myosin head.

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Correct Answer

Step-by-Step Solution

Explanation

How the Examiner Thinks

Regulatory_Failure

Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.

Concepts Behind This Question

Mitochondrial_Respiration|ATP_Synthase|10_Percent_Law

Why This Question Is Tricky

Common Mistakes

Conceptual Pivot: Students often memorize 'lactic acid causes fatigue' without understanding the molecular mechanism (pH drop affecting protein conformation and Ca2+ binding).

Additionally, this question tests the 'Common Misconception' regarding the role of ATP in muscle contraction; students frequently assume ATP is needed to form the cross-bridge, whereas NCERT clearly states ATP binding causes the cross-bridge to detach.

Quick Facts About This Question

Question Information

SubjectBiology
ChapterLocomotion and Movement - Class 11
ConceptCross-bridge Cycling Energy
Difficulty8
Cognitive Load5
Target Solve Time120 sec
AccessFree