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Question #45861
The Question
Which of the following statements is INCORRECT regarding the experiments that established the biochemical nature of the genetic material?
Options
- A.
Digestion of the heat-killed S-strain extract with RNases or proteases does not inhibit the horizontal gene transfer to the live R-strain.
- B.
DNase halts the transformation of the non-virulent R-strain by hydrolyzing the hydrogen bonds of the transforming principle.
- C.
In the Hershey-Chase experiment, agitation in a blender was utilized to separate the 35S-labeled viral protein coats from the bacterial cells.
- D.
The unequivocal proof that DNA is the genetic material was established by showing that 32P-labeled bacteriophage DNA entered the host cell.
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Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Regulatory_Failure
Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.
Concepts Behind This Question
Griffith’s Transforming Principle|Hershey-Chase Isotopic Labeling|DNA Polymerase
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: Students often know that DNase 'destroys' DNA to prevent transformation, but they fall for the micro-terminology trap regarding the exact bond broken.
They confuse the hydrolysis of the covalent phosphodiester backbone (by nucleases) with the breaking of weak hydrogen bonds (by helicases or denaturation).
This requires synthesizing 'Enzyme Action' from Biomolecules with the 'Molecular Basis of Inheritance'.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Molecular Basis of Inheritance - Class 12 |
| Concept | Griffith’s Transforming Principle |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |