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Question #46345

Difficulty: 8/10 | 🟢 Free

The Question

A 2-year-old child diagnosed with Kwashiorkor exhibits severe systemic edema and ascites. Based on the physiological roles of major plasma proteins, which of the following mechanisms directly explains this extensive fluid accumulation in the interstitial spaces?

Options

  • A.

    Increased blood capillary hydrostatic pressure at the arterial end due to compensatory cardiovascular mechanisms.

  • B.

    Decreased hepatic synthesis of albumins, leading to a drop in blood colloidal osmotic pressure and reduced fluid reabsorption at the venous end.

  • C.

    Depletion of plasma globulins, which normally maintain the osmotic balance and prevent fluid leakage across the capillary endothelium.

  • D.

    Increased permeability of lymphatic capillaries due to tissue degeneration, resulting in the accumulation of lymph in the extracellular space.

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Correct Answer

Step-by-Step Solution

Explanation

How the Examiner Thinks

Regulatory_Failure

Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.

Concepts Behind This Question

Albumin|BCOP|Interstitial_Fluid_Accumulation

Why This Question Is Tricky

Common Mistakes

Conceptual Pivot: Linking a nutritional deficiency (Kwashiorkor) to a specific plasma protein's function (Albumin) and its physical consequence (Edema via Starling's forces).

The common misconception is confusing the roles of the three major plasma proteins (Fibrinogen for clotting, Globulins for defense, Albumins for osmotic balance) or misunderstanding that this specific edema is caused by a failure to pull fluid back into the blood, rather than an active pushing of fluid out.

Quick Facts About This Question

Question Information

SubjectBiology
ChapterBody Fluids and Circulation - Class 11
ConceptPlasma Proteins and Osmotic Pressure
Difficulty8
Cognitive Load5
Target Solve Time120 sec
AccessFree