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Question #46358

Difficulty: 8/10 | 🟢 Free

The Question

Read the following statements regarding the genetic and evolutionary basis of human blood group systems. Which of the following statements is INCORRECT?

Options

  • A.

    The structural variation between A and B antigens on the RBC membrane is due to different alleles of gene I encoding slightly different glycosyltransferase enzymes.

  • B.

    The antigenic polymorphism observed in the ABO blood group system is a direct phenotypic consequence of the degeneracy of the genetic code.

  • C.

    Despite the selective pressure of maternal-fetal incompatibilities, multiple alleles of the ABO system are maintained in the population via balancing selection.

  • D.

    Erythroblastosis fetalis occurs when maternal anti-Rh antibodies, which are of the IgG class, cross the placental interface and destroy fetal Rh+ erythrocytes.

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Correct Answer

Step-by-Step Solution

Explanation

How the Examiner Thinks

Evolutionary_Exception

Tackle problems where standard rules evolve or change based on specific environmental constraints.

Concepts Behind This Question

ABO-Rh Incompatibility Logic|Genetic Code Degeneracy|Multiple_Alleles

Why This Question Is Tricky

Common Mistakes

Conceptual Pivot: Students often conflate 'Degeneracy of the genetic code' (redundancy at the nucleotide level yielding the SAME protein) with 'Multiple allelism/Polymorphism' (variation at the genomic level yielding DIFFERENT proteins/phenotypes).

The trap relies on the student misinterpreting 'degeneracy' as a source of variation rather than a buffer against it.

Quick Facts About This Question

Question Information

SubjectBiology
ChapterBody Fluids and Circulation - Class 11
ConceptABO-Rh Incompatibility Logic
Difficulty8
Cognitive Load5
Target Solve Time120 sec
AccessFree