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Question #46423
The Question
Read the following statements regarding the replication cycle of retroviruses and their genetic integration. Which of the following statements is INCORRECT?
Options
- A.
Retroviruses employ an RNA-dependent DNA polymerase to synthesize a complementary DNA strand, modifying the unidirectional flow of the Central Dogma.
- B.
The viral DNA integrates into the host cell's genome to form a provirus, which then directs the infected cell to produce viral RNA.
- C.
The integrated provirus replicates autonomously in the host cytoplasm, independent of the host's genomic replication machinery.
- D.
If integration occurs in host germline cells, the viral genetic blueprint can be inherited by subsequent generations as an endogenous retroelement.
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Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Evolutionary_Exception
Tackle problems where standard rules evolve or change based on specific environmental constraints.
Concepts Behind This Question
HIV Replication Cycle|Reverse Transcriptase|Retroviruses
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot & Location Trap: Students often confuse the location of reverse transcription (which occurs in the cytoplasm) with the location of the provirus (which must be in the nucleus).
Furthermore, they confuse the autonomous replication of plasmids or certain cytoplasmic RNA viruses with the obligate, host-dependent nuclear replication of a retroviral provirus.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Evolution - Class 12 |
| Concept | Abiogenesis vs. Biogenesis |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |