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Question #46725
The Question
In an in vitro experiment, the plasma membranes of ovarian follicle cells are artificially depleted of cholesterol, significantly decreasing the lateral mobility of integral membrane proteins. If these cells are subsequently exposed to Follicle Stimulating Hormone (FSH), which of the following steps in the signaling cascade will be most directly and immediately impaired?
Options
- A.
The initial binding of FSH to the extracellular domain of its specific membrane-bound receptor.
- B.
The collision-coupling between the activated FSH receptor and the membrane-bound G-protein.
- C.
The catalytic activation of Adenylate Cyclase and the subsequent generation of cAMP.
- D.
The translocation of the FSH-receptor complex into the nucleus to regulate gene expression.
Check Your Answer
Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Comparative_Analysis
Sharpen your ability to evaluate multiple scenarios and distinguish between competing potential answers.
Concepts Behind This Question
Plasma_Membrane_Fluidity|cAMP|Protein_Kinase_A
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: Students often memorize the biochemical sequence of secondary messenger cascades (Hormone -> Receptor -> G-protein -> cAMP) without integrating the structural prerequisite of the cell membrane (Fluid Mosaic Model).
The trap lies in distinguishing between the direct physical consequence of reduced membrane fluidity (failure of receptor-G-protein collision) versus downstream biochemical consequences (failure of cAMP production) or fundamental misconceptions about hormone types (steroid vs. peptide entry).
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Cell – The Unit of Life - Class 11 |
| Concept | Plasma Membrane Fluidity |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |