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Question #47444
The Question
A patient develops a localized autoimmune condition that specifically degrades Type II collagen in the inner ear, leading to a significant decrease in the overall stiffness of the basilar membrane. The vestibulocochlear nerve (CN VIII) remains completely intact. Based on the place theory of hearing, which of the following is the most likely physiological consequence of this structural alteration?
Options
- A.
The point of maximum basilar membrane vibration for a given frequency will shift distally towards the apex, resulting in pitch perception dissonance.
- B.
High-frequency sounds will continue to resonate at the narrow, basal end, but the amplitude of the resulting action potentials will be significantly reduced.
- C.
Low-frequency sound waves will prematurely reach their resonance peak at the base of the cochlea due to the overall loss of membrane tension.
- D.
Mechanotransduction will cease entirely because the stereocilia of the hair cells will no longer shear against Reissner's membrane.
Check Your Answer
Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Regulatory_Failure
Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.
Concepts Behind This Question
Organ of Corti|Basilar Membrane|Type II Collagen
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: Pitch perception is dictated by the mechanical stiffness gradient of the basilar membrane, not just neural wiring.
Common Misconception: Students often memorize the static tonotopic map (base = high, apex = low) without understanding the biophysical 'Why'.
By altering the physical stiffness, the entire tonotopic map shifts.
Furthermore, Option D exploits a common anatomical confusion between the membranes of the cochlea (Reissner's vs.
Tectorial), and Option B traps students who confuse stimulus intensity with action potential amplitude.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Neural Control and Coordination - Class 11 |
| Concept | Cochlear Frequency Coding |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |