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Question #47454
The Question
A male patient with a normal karyotype presents with infertility caused by a localized lesion disrupting the hypothalamic pulse generator. Assuming a few spermatids still manage to form, which of the following structural or biochemical deficiencies in the resulting spermatozoa is a direct physiological consequence of this specific neuro-endocrine failure?
Options
- A.
Defective packaging of hydrolytic enzymes in the Golgi-derived acrosomal vesicle due to diminished Leydig cell stimulation.
- B.
Impaired flagellar motility caused by the inability of the mitochondrial sheath to utilize epididymal fructose.
- C.
Arrest of meiotic division in primary spermatocytes due to the absence of Sertoli cell-derived androgens.
- D.
Inability to undergo capacitation due to a genetic mutation altering the receptors on the sperm plasma membrane.
Check Your Answer
Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Regulatory_Failure
Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.
Concepts Behind This Question
LH|Testosterone|Spermatogenesis|Acrosin
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: Students often memorize the HPG axis and sperm structure as isolated facts.
This question requires synthesizing them: recognizing that a central endocrine failure (low testosterone) directly impairs subcellular morphological changes during spermiogenesis (acrosome formation).
It also utilizes 'Location/Source Traps' by misattributing fructose to the epididymis and androgens to Sertoli cells, testing precise NCERT factual recall.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Neural Control and Coordination - Class 11 |
| Concept | Hypothalamic-Pituitary Axis Integration |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |